A crash disrupted traffic on US 93, the primary driving route between Phoenix and Kingman, for several hours on Tuesday.
The Arizona Department of Transportation says all lanes of U.S. 93 are reopened after a couple of big crashes.
The three-vehicle crash has resulted in serious injuries and the closure is expected to last for an extended period of time.
Emergency responders have cleared the scene of an injury crash involving a semitruck and a car along U.S. Highway 93.
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