Amide bonds are common in drugs because they are chemically stable, form readily and are biocompatible. They also help ...
A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid without ...
A recent study posted to the bioRxiv* pre-print server investigated the antiviral potential of N-acylethanolamine acid amidase (NAAA) against severe acute respiratory syndrome coronavirus 2 ...
A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl ...
The authors’ approach is deceptively simple: take an aldehyde dehydrogenase enzyme, which naturally converts aldehydes to acids, and get it to react with an amine instead of water. But actually making ...
Hyperactivation of the amygdala following chronic stress is believed to be one of the primary mechanisms underlying the increased propensity for anxiety-like behaviors and pathological states; however ...
Editor's Note: The paper, Asymmetric remote C–H borylation of aliphatic amides and esters with a modular iridium catalyst, was published in the journal Science, and will be withdrawn at 14.00 EDT on ...
Spun out of MIT, Amide partners with biopharmas to accelerate peptide drug development – shortening synthesis to days instead of months – with peptides 3x longer than existing methods CAMBRIDGE, Mass.
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