Engineered BiTE molecule draws T cells to eliminate FAP+ modulated smooth muscle cells, reducing plaque burden across mouse atherosclerosis models.

Scientists have designed an immunotherapy that reduces plaque in the arteries of mice, presenting a possible new treatment strategy against heart disease. The antibody-based therapy could complement ...

This is a preview. Log in through your library . Abstract Near confluent monolayers of arterial smooth muscle cells derived from Macaca nemestrina were labeled with Na2[35 S] O4 and the newly ...

Scientists have designed an immunotherapy that reduces plaque in the arteries of mice, presenting a possible new treatment strategy against heart ...

We have constructed an in vitro arterial wall model by coculturing bovine arterial endothelial cells (ECs) and smooth muscle cells (SMCs). When ECs were seeded directly over SMCs and cocultured in an ...

New findings show how the progression of atherosclerosis is affected by a combination of hypertension and changes to the stiffness of the artery. Research published in Science Advances discovers the ...

Scientists have discovered the protective role played by identity-morphing cells -- and the gene behind them -- in atherosclerosis, according to a new study. Changing your identity to protect others ...

Yabing Chen, Ph.D., has been awarded two National Institutes of Health grants totaling more than $5 million to further her research into vascular diseases ranging from hardening of the arteries to ...

Changing your identity to protect others might sound like something reserved for comic book vigilantes, but a study led by researchers at the Stanford University School of Medicine has found a select ...