The complement system is part of the body's immune system to fight pathogens and remove cell debris; its role in two autoimmune diseases and a mental disorder is a surprise Variants in a gene of the ...

Complement component 3, often called C3, is an essential protein of the immune system. This protein plays a vital role in the body’s innate immune system, providing: the first line of defense against ...

A prospective cohort study evaluating complement and platelet activation among lupus patients with antiphospholipid syndrome. Problem: There is a high rate of obstetrical complications, such as ...

Share on Facebook. Opens in a new tab or window Share on Bluesky. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window A commercially ...

Restoring the bodys balance between the actions of antibodies and natural regulatory proteins is the goal of a therapy being developed for the autoimmune disease lupus. This treatment thwarts ...

Most people with lupus have antinuclear antibodies (ANAs) in their blood. But a positive ANA test doesn’t always mean lupus. The test can be positive in people with other autoimmune illnesses — ...

A complement C4 (also known as a complement component 4, or simply C4) is a test to measure the level of C4 proteins you have in your blood. These proteins play a role in how your immune system ...

A gamma-globulin factor in the serum of patients with systemic lupus erythematosus that reacts with isolated cell nuclei 1 or nucleoprotein 2,3 has been detected in many ways. 4 The standard method of ...

It was called ‘complement’ because it aided the antibacterial activity of antibodies. However, it is now known that the complement system can be activated early in an infection without the presence of ...

New research identifies age, anti-β2GP1 antibodies, and low complement C3 as key risk factors for cerebral small vessel disease in systemic lupus erythematosus.