The US Food and Drug Administration (FDA) has granted Fast Track Designation to Complement Therapeutics’ CTx001, the ...

Complement Therapeutics GmbH (CTx), a clinical-stage biotechnology company developing next-generation therapeutics for complement-mediated diseases, today announced that the U.S. Food and Drug ...

Global understanding of complement has shifted and developed since the 21st century: from our idea of a blood-based antibiotic system to a global regulator of immunity and tissue homeostasis. Recent ...

When drug development and the immune system collide we get CAR-T, checkpoint inhibitors, oncolytic vaccines, monoclonal antibodies and more. These fields have produced many therapies and garnered a ...

Frequent kidney dialysis can cause systemic inflammation, leading to complications such as cardiovascular disease and anemia by triggering the complement cascade, part of the innate immune system.

The complement system maintains tissue homeostasis and integrity and forms the first central and immediately acting line of defence against invading infectious microorganisms. Complement activation ...

It was called ‘complement’ because it aided the antibacterial activity of antibodies. However, it is now known that the complement system can be activated early in an infection without the presence of ...

November 21, 2011 — The cartilage damage associated with osteoarthritis (OA) is in part a result of dysregulation of the complement system, Qian Wang, MD, PhD, and colleagues reported in an article ...