RNA aptamers are short, single-stranded oligonucleotides that adopt unique three-dimensional structures, enabling them to bind selectively to fluorogenic dyes and other small molecules. Engineered to ...

Researchers have figured out a way to make an RNA biosensor that fluoresces when it encounters small inorganic metabolites—not by engineering the RNA but by adjusting its fluorogenic ligand molecule.

Continuous monitoring of biomarkers is essential for early disease detection, treatment evaluation, and personalized health ...

Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, biosensing, DNA origami integrity reporting, and reusable mRNA detection through ...