Largest FDA-authorized Phase 2 cell therapy trial conducted in chronic lumbar disc diseaseThe study has enrolled a total of 99 participants, each ...
Lumbar disc herniation refers to the condition in which one of the discs in the lower back (lumbar spine) protrudes or ruptures. The lumbar spine consists of a stack of bones called vertebrae ...
This integrated approach, combining histological analysis and single-nucleus RNA sequencing, revealed that the senescence and depletion of nucleus pulposus progenitor cells (NPPCs) represent ...