Acute myeloid leukemia (AML) impairs neutrophil maturation in bone marrow, with mature neutrophils decreasing by over 78% in marrow and 89% in blood. AML-exposed neutrophils acquire inflammatory ...
An international research collaboration mapped the glycosylation of proteins from both maturing and mature neutrophils, a type of white blood cell that responds to tissue injury and infection. Their ...
Emergency hemopoiesis may maintain blood counts and a proinflammatory environment in MDS, AML, and ICUS. Altered neutrophil subset distributions in MDS and AML show diagnostic sensitivity, with ...
Two proteins ensure that cells can take up iron when needed. If both control proteins are switched off in mice, the animals develop severe anemia, as expected. At the same time, surprisingly, a cell ...
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How tumor stem cells hijack neutrophils to evade immunotherapy
Researchers at the University of Chicago recently revealed that a small group of cancer cells, known as tumor-initiating stem cells (tSCs) hijack nearby neutrophils, turning them from attackers into ...
Results open the door to therapies based on chronobiology, the branch of biology that studies how living organisms structure their physiological processes in time.
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