Potassium channel blockers are a type of medication used to treat conditions like cardiac arrhythmias. They block the movement of potassium channels in the body, disrupting the body’s electrical ...

Orphan Drug Designation applies to approximately 50,000 Patients who predominantly suffer from severe chronic pain due ...

Dr. Naccarelli answers the question: 'What Is Sotalol, How Does It Work?' — -- Question: I have been placed on an antiarrhythmic drug called sotalol for my heart rhythm problem. How does it work ...

Researchers have discovered a new mechanism for potassium channel inhibitor entry, which could improve the specificity of drugs targeting the channel. Upon binding to calcium ions, BK channels allow ...

Potassium channels are essential membrane proteins that enable the selective and rapid transport of K⁺ ions, a process fundamental to cellular excitability and signal transduction. Recent research has ...

A study conducted by researchers at the Center for Redox Processes in Biomedicine (Redoxoma) has shown that ATP-sensitive mitochondrial potassium channels (MitoK ATP) are involved in both the ...

This article and associated images are based on a poster originally authored by Sivakumar, M, Smith, E, Shumate, J, Scampavia, L, Spicer, T, Hernandez, D and Peters, C and presented at ELRIG Drug ...

Researchers find blocking the KCNB2 gene can slow tumor growth, paving the way for next-gen treatments for childhood brain cancer. Scientists at The Hospital for Sick Children (SickKids) have ...

A study published in the 19 October Nature shows that one subunit of a potassium channel has a pivotal role in controlling vascular smooth muscle tone. This raises the possibility that defects in this ...

Voltage-gated potassium (Kv) channels play an important role in modulating the electrical activity of cells, opening in response to changes in membrane voltage and allowing potassium ions to escape.