The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA). 1 There are four key steps in the RNAi pathway. When miRNA acts as the guide for RNAi, only a ...

BERKELEY, CA -- An organelle called the nucleolus resides deep within the cell nucleus and performs one of the cell's most critical functions: it manufactures ribosomes, the molecular machines that ...

In the first published real use of high-throughput RNAi screening in a laboratory setting, a group of researchers at the University of California, San Francisco, has identified novel negative and ...

A Cornucopia of siRNA- and RNAi-based Therapeutics in Development Show Promise Researchers from academia and industry will present the latest developments in the application of interference RNA (RNAi) ...

Historically, most therapeutics have been small chemicals and antibodies designed to target cellular proteins. New kinds of therapeutics are emerging, however, from a better understanding of noncoding ...