Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation. Retrotransposons ...

Figure 2. Diagrammatic representation of kodikaz therapeutic solutions’ zip-code technology application to various human diseases. The complex interplay between extracellular genetic material and the ...

A joint research group team led by Sayuri Tsukahara and Tetsuji Kakutani of the University of Tokyo has clarified a mechanism of how retrotransposons, genetic elements that can "jump around" ...

Inflammasomes are huge, multi-protein complexes inside cells that spark inflammation when they sense danger. Inflammasomes can also sound the alarm when no pathogens are present, contributing to ...

Long Interspersed Nuclear Element-1 (LINE-1 or L1) is the only active, self-copying genetic element in the human genome—comprising about 17% of the genome. It is commonly called a "jumping gene" or ...

The Ty1 retrotransposon, an LTR element intrinsic to Saccharomyces cerevisiae, plays a pivotal role in genome evolution through its dynamic replicative cycle and interactions with host cellular ...

Retrotransposons are evolutionarily ancient genes that “jump” around the human genome leaving a slew of repeat nucleotide sequences in their wake. These repeats can disturb normal gene function.

Researchers demonstrated that the microscopic worm C. elegans uses a retrotransposon called Cer1 to transfer a learned behavior (avoidance of a pathogenic bacterium) between worms. In earlier work, ...

Like its viral cousins, a somewhat parasitic DNA sequence called a retrotransposon has been found borrowing the cell's own machinery to achieve its goals. In a new work appearing online Wednesday in ...

Researchers have provided the first direct evidence that an evolutionarily conserved, retrotransposon-derived gene is essential for embryonic development, at least in mice, according to a study ...