For decades, aging has looked like a one-way street, a slow accumulation of damage written into our cells. Now a wave of ...

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes. The breakthrough ...

New scientific methods could one day render animal studies—the standard in research laboratories for more than 100 years—obsolete. Clive Svendsen, Ph.D., executive director of the Board of Governors ...

Collaborative research defines a novel approach to understanding how certain proteins called transcription factors determine which genetic programs will drive cell growth and maturation. The method, ...

A 25-year-old woman with type 1 diabetes started producing her own insulin less than three months after receiving a transplant of reprogrammed stem cells 1. She is the first person with the disease to ...

A woman with Type 1 diabetes who was treated with her own stem cells subsequently started producing insulin on her own, making her the first person with this type of diabetes to reverse her condition ...