Continuous roller compaction has been a well-established method in the pharmaceutical business for decades, and it is used for more than just moisture and temperature-sensitive products. Unlike ...

Although tablet manufacture is traditionally a batchbased wet granulation process, there are many advantages to be gained by adopting dry granulation, including lower costs and increased yields.

Using a novel automated microfilling system, the authors demonstrate that roller compaction followed by milling is a viable preprocessing technique for high-dose chemical-in-capsule dosage forms. The ...