Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...
Researchers create a massive single-cell atlas of the aging mouse brain, revealing how epigenetic changes and "jumping genes" drive neurodegeneration.
Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to ...
Van Andel Institute scientists develop technique for high-resolution single cell epigenetic analysis
GRAND RAPIDS, Mich. (July 15, 2025) — Van Andel Institute scientists have developed an improved technique to comprehensively profile DNA methylation in single cells, an advance that will help ...
Single-cell sequencing is useful for a number of applications. For example, it can reveal cellular heterogeneity inside complex tissues, such as tumors. It can also provide information about how ...
Different cell types typically express unique genes to help them differentiate into their assigned roles—skin cells express genes for skin while liver cells express genes for liver and so on. However, ...
Cancer biology increasingly recognizes that cancer stem cells (CSCs) represent a critical subpopulation within tumors, marked by their self-renewal, ...
Our genetic code is shaped by our surroundings, diet, where we live, our activities, and many other factors. When these influences do not alter our ...
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