Assessments of DNA misrepair, and the resulting effects on the structural integrity of the genome, are critical for evaluating the safety of cell and gene therapy applications. Most genome editing ...

This illustration shows proteins and DNA in the process of DNA repair. RecA proteins (gold) cradle a single-stranded DNA (brown) that searches for homology with a DNA template (purple). The template ...

Changes in genes have been linked to the development of different diseases for a while. However, it's not exactly clear what ...

Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied. A quirk of linear DNA replication dictated that telomeres ...