A more-nuanced approach to reporting and interpreting data from randomized controlled trials, one that factors in the totality of the evidence, is warranted in cardiovascular medicine, according to a ...

The pursuit of science is designed to search for significance in a maze of data. At least, that’s how it’s supposed to work. To support or refute a hypothesis, the goal is to establish statistical ...

WASHINGTON – This year's edition of Transcatheter Cardiovascular Therapeutics offered a host of sessions addressing clinical trial design and data, but one of the more thought-provoking sessions may ...

The proverbial searching for "the needle in a haystack" can help us understand science's problem with p-values, and why so many studies find contrary things. Science and medicine often deal with ...

For researchers there's a lot that turns on the p value, the number used to determine whether a result is statistically significant. The current consensus is that if p is less than .05, a study has ...

Your editorial “The FDA Returns to Its Bad Habits” (Feb. 21) explains, “Reata’s p-value was 0.014, which means there was a 1.4% chance that its positive result was a fluke.” A related, true statement ...