This systematic review and meta-analysis identified prognostic factors associated with early mortality in septic shock. The identification of these prognostic factors could aid in clinical risk ...

A new publication in Nature Reviews Methods Primers provides essential guidance for conducting rigorous systematic reviews on studies with animals and cells. It also highlights the benefits of these ...

Background While female sex has historically been associated with worse outcomes following surgical aortic valve replacement, ...

Objective This systematic review aims to evaluate the effectiveness of exercise interventions in alleviating depression and ...

Despite rapid advances in large language models, this study shows that human expertise remains critical for producing rigorous systematic reviews, with AI best suited as a supervised support tool ...

A major new scientific review brings reassuring news for expectant parents: using acetaminophen, commonly known as Tylenol, during pregnancy does not increase a child’s risk of autism, ADHD, or ...

Early communication regarding prognosis and goals of care is crucial to ensuring a patient-centred approach to managing high-risk conditions such as septic shock. Identifying people at risk of poor ...

An ad hoc committee of the National Academies of Sciences, Engineering, and Medicine will produce a report to update the standards for systematic reviews as defined in the 2011 report Finding What ...

Objective To synthesise data on the associations between cardiorespiratory fitness (CRF) and health in children and adolescents, evaluate the certainty of evidence and identify knowledge gaps. Design ...