The inflammatory tumor microenvironment (TME) is a complex network of cancer, immune, and stromal cells interacting through cytokines and growth factors to drive tumor growth, angiogenesis, and immune ...

The tumor microenvironment (TME) consists of mediators surrounding a tumor, including diverse cell types, blood vessels, and other cellular components. Certain elements of the TME can benefit patients ...

Up to 20% of hormone receptor-positive breast cancers don't respond to antiestrogen therapies. A study led by researchers at ...

Among the presentations included in the Top Abstracts category at the recently inaugurated Annual Congress of the European Association for Cancer Research (EACR) in Lisbon, it is worth highlighting ...

A gene expression program executed by neutrophils and a corresponding biomarker support tumor progression across human and murine tumors.

Over the past decade, the advent of immune checkpoint blockade (ICB) therapy has transformed cancer treatment. Unlike conventional cytotoxic and targeted therapies, immunotherapy leverages both the ...

Despite progress in cancer biology, deciphering the spatial architecture of the tumor microenvironment remains a challenge. Traditional approaches lack the resolution to map cell-type-specific gene ...

Renowned as first responders to threatening infections, neutrophils also happen to feature prominently in the ...

Cancer nanotechnology stands at the forefront of nanobiotechnology, drawing together innovation from materials science, engineering, and the biomedical ...

Study results indicate that mutation strength may shape both tumor–immune system interactions and immunotherapy response.