Kickoff from U.S. Bank Stadium in Minneapolis is set for 4:30 p.m. ET. The latest Vikings vs. Lions odds have Detroit favored by 7 points, while the over/under for total points scored is 44.5 via DraftKings Sportsbook. Before making any Lions vs. Vikings picks, check out the NFL predictions from the SportsLine Projection Model .

If Los Angeles pulls this off, it will have the hardest-won division title in recent memory. At 11-4, they can steal the AFC West from the Broncos by winning out, despite Denver rattling off 11 straight wins from Week 4 to Week 15. Unfortunately for the Chargers, they couldn’t be less equipped to face the two teams they have to beat.

In 2026, the Giants will undergo another major rebuild. For better results, here are five top draft prospects who could help the brain trust get it right this time.

The Denver Broncos and Kansas City Chiefs clash Christmas night. Kickoff for Thursday Night Football is at 8:15 p.m. ET in Kansas City, Missouri.

Each pick has a confidence level of 1-10, with 10 being the most confident. For more information on the pick methodology, check out the Week 1 edition of this series. Keep in mind that since the idea here is to make high-percentage plays,