Researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery. Our immune system is armed with an array of defenses designed to detect and ...

Acute systemic inflammation has long been suspected to trigger harmful processes within the brain, contributing to ...

Surely, inflammation is half a billion years old, since even the lowly starfish may experience it. Virtually every human being who ever lived has suffered from it, perhaps dozens or hundreds of times.

Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal conditions, these cells act ...

New findings identify CASP4/11 as detrimental to inflammation and coagulopathy associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Researchers recognize CASP4/11 as ...

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system—a group of proteins that ...