Introduction Dyspnoea is an existentially burdensome symptom in patients with advanced and progressive diseases such as cancer, chronic obstructive pulmonary disease (COPD) and advanced heart failure.

BACKGROUND: BCR-ABL tyrosine kinase inhibitors (TKIs) have been increasingly linked to pulmonary arterial hypertension (PAH) since 2009, although supporting evidence is limited. Our objective was to ...

In this nationwide cohort study, trans Australians experienced substantially elevated mortality risk. Tailored policy responses are needed to address premature mortality in trans populations.

Wulandari, Rastafael, and Hwihanus (2024) conducted a meta-analysis of international studies and found that implementing ...

Objectives Among young offenders, psychiatric morbidity and comorbidity are common, but our knowledge about their use of mental health services during childhood and adolescence is scarce. We aimed to ...

A multicolored 3D model of an enzyme binding double-stranded DNA against a light purple background Computational enzyme design could allow for reactions not seen in nature. Credit: Ian Haydon ...

In the current climate, generic and expensive programs to promote diversity, equity, and inclusion—for example, trainings—are increasingly falling out of favor. In fact, most of the existing research ...

Recent Trends and Patient Outcomes of Phase I Trials: A Single-Institution Experience in the Era of New Therapeutic Agents This study reviewed all industry-sponsored phase I clinical trial protocols ...

The Design-Build model is an increasingly attractive project delivery method, offering benefits such as enhanced control, reduced risks, cost efficiencies, and quicker completion times. Central to ...

Section 1. Purpose and Policy. America has long led the world in innovation, technological advancement, and design. But with a sprawling ecosystem of digital services offered to Americans, the ...

Design thinking stands out as a methodology that promotes creativity, user-oriented approach and interdisciplinary collaboration and has emerged as an active teaching methodology that encourages the ...