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  1. Squamous Intraepithelial Lesion (SIL): Causes & Treatment

    High-grade (HSIL). High-grade SILs include moderate dysplasia, severe dysplasia and neoplasia in-situ (the last phase before tissue becomes cancerous). These lesions look very abnormal …

  2. High Grade Squamous Intraepithelial Lesion (HSIL) - Verywell …

    Nov 9, 2025 · High-grade squamous intraepithelial lesion (HSIL) signals moderate to severe abnormal changes in cervical cells, which can increase the risk of cervical cancer. …

  3. Definition of high-grade squamous intraepithelial lesion - NCI ...

    High-grade squamous intraepithelial lesions look somewhat to very abnormal when looked at under a microscope. They are usually caused by chronic infection with certain types of human …

  4. What Is a High-Grade Squamous Intraepithelial Lesion?

    Jul 25, 2025 · A high-grade squamous intraepithelial lesion, often abbreviated as HSIL, identifies abnormal cell changes found on the surface of organs, most commonly the cervix. This means …

  5. What is high grade squamous intraepithelial lesion (HSIL)?

    High grade squamous intraepithelial lesion (HSIL) is a precancerous condition caused by infection with human papillomavirus (HPV). It involves abnormal changes in squamous cells, which are …

  6. Patient education: Follow-up of high-grade or glandular cell ... - UpToDate

    High-grade squamous intraepithelial lesions (HSIL) refer to moderate to severe changes in the cells of the cervix. If less severe changes are seen, this is called low-grade squamous …

  7. Pathology Outlines - HSIL / CIN II / CIN III

    Sep 17, 2025 · Precancerous squamous proliferative lesion with full thickness nuclear atypia and varying degrees of cytoplasmic maturation; driven by high risk HPV subtypes.

  8. Squamous intraepithelial lesion - Wikipedia

    A squamous intraepithelial lesion (SIL) is an abnormal growth of squamous cells on the surface of the cervix; normal squamous cells make up the normal epithelium of the cervix. This lesion …

  9. Squamous intraepithelial lesions (SIL: LSIL, HSIL, ASCUS, ASC …

    This review provides the key cytologic features that distinguish Bethesda squamous categories from other important entities, using algorithmic approach and illustrations of common …

  10. High-grade squamous intraepithelial lesion - Libre Pathology

    Aug 13, 2015 · High-grade squamous intraepithelial lesion, abbreviated HSIL, is a pre-cancerous lesions of the uterine cervix. Increasingly, the term is being applied to other anatomical sites, …